RNAi at the CS Department, UNM

Gene Family Knockdown

with RNA Interference (RNAi) via Set Cover Optimization

Target Genes and Organism

Number of siRNA Covers:	1 2 3 4 5
Select Target Organism:	B. glabrata S. pombe C. elegans H. sapiens
Select Target Genes:
Off-target Filtering:	on

Note that: the Gene Family Knockdown (GFK) program allows users to design optimal siRNA covers with high predicted silencing efficacy, which can be used to simultaneously knock down a set of target genes (i.e., gene family) in an organism. siRNA silencing efficacy (i.e., rank) is predicted based on Reynolds' rational design rules.